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Easy Keto Low-Carb Pizza Casserole

Easy Keto Low-Carb Pizza Casserole is a quick healthy recipe perfect for meal prep. This dish is baked with cream cheese, pepperoni, and ground beef, a great crustless pizza substitute. 

keto low carb pizza casserole in a red dish with a red napkin
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The idea for this casserole came to me for a few reasons. For starters, I see a lot of people who are following a keto diet, post that they eat the cheese and toppings off their pizza and they toss out the crust.

eggs, chopped onions, cream cheese, garlic, and cream for keto low carb pizza casserole

This is a huge waste of food, this casserole is BETTER and won’t waste a bunch of food! I also have a thing for casseroles and I have several popular dishes on the site.

If you are looking for a breadless option with no crust that is made without cauliflower, keep scrolling my friend!

If you’re looking for more keto pizzas, check out my Keto Low-Carb Bacon Chicken Alfredo Pizza and Keto Fathead Pepperoni Pizza.

raw ground beef and uncured pepperoni for keto low carb pizza casserole

Key Ingredients

  • Ground Beef (I use organic, grass-fed)
  • Pepperoni (I use uncured, nitrate-free)
  • Marinara Sauce (No-sugar added)
  • Mozzarella Cheese
shredded mozzarella cheese and marinara for keto low carb pizza casserole

How to Make Keto Pizza Casserole

  1. Combine onions and garlic.
  2. Add in ground beef and seasoning. Next add cream cheese and marinara.
  3. Create a binder for the casserole using heavy cream, eggs, and mozzarella.
  4. Layer the gound beef mixture into a casserole dish.
  5. Cover with the binder, additional cheese, and pepperoni.
  6. Bake.
chopped onions, ground beef, cream cheese, and marinara cooked in a skillet for process photos showing how to layer keto low carb pizza casserole
heavy cream, eggs, and mozzarella for keto low carb pizza casserole
process photos showing how to layer keto low carb pizza casserole in a red dish
process photos showing how to layer keto low carb pizza casserole in a red dish

How Many Calories and Carbs

This dish has 449 calories and 4 net carbs per serving.

keto low carb pizza casserole in a red dish with a red napkin

How Long Will it Last in the Fridge

The casserole will last for 3-4 days (covered) in the refrigerator.

keto low carb pizza casserole in a red dish with a red napkin

Can You Make the Casserole Ahead of Time?

You can make most of the casserole ahead of time. You can cook the ground beef and the cream cheese and marinara.

If you plan to make the dish ahead I do not recommend you add the cream and eggs. Save that, along with the shredded cheese for right before you bake the dish in the oven.

keto low carb pizza casserole in a red dish with a red napkin

Is it Freezer Friendly?

Cream isn’t usually an ingredient you want to freeze. I have frozen this casserole, fully cooked. Upon reheating, it was still good, but it did not taste as good as it would if you eat it within a few days.

Casserole Substitution Tips

You can make changes to this dish and switch it up however you like. If you omit the eggs, your casserole will likely fall apart very easily. You can not taste the eggs in this recipe.

  • Ground Turkey
  • Bacon
  • Chicken
  • Green Peppers
  • Olives
  • Mushrooms

Pair With these Side Dishes

Green Goddess Salad
Pepperoni Chips
Avocado Egg Salad Cups
Grilled Asparagus in Foil

More Keto Casserole and Popular Recipes

Keto Low-Carb Cheeseburger Casserole
Keto Low-Carb Philly Cheesesteak Casserole
Keto Low-Carb Bacon, Egg Casserole

Big Mac Casserole
Keto Onion Rings

Keto Smothered Pork Chops

You can make Homemade Marinara Sauce using my recipe here. You can also drizzle it with my Homemade Keto Ranch Salad Dressing.

keto low carb pizza casserole in a red dish with a red napkin
Print Pin
4.88 from 31 votes

Easy Keto Low-Carb Pizza Casserole

Easy Keto Low-Carb Pizza Casserole is a quick healthy recipe perfect for meal prep. This dish is baked with cream cheese, pepperoni, and ground beef, a great crustless pizza substitute. 
Save this recipe here.
Course dinner, lunch
Cuisine American
Keyword keto crustless pizza, keto pizza casserole, low carb pizza casserole
Prep Time 15 minutes
Cook Time 25 minutes
Total Time 40 minutes
Servings 6
Calories 449kcal

Ingredients

  • 1 teaspoon olive oil
  • 1/2 cup chopped onions
  • 2 garlic cloves
  • 1 pound ground beef
  • 1 teaspoon Italian Seasoning
  • Salt and pepper to taste
  • 1 cup marinara sauce I recommend Raos or you can make homemade marinara using the recipe linked above in the blog post.
  • 2 oz cream cheese
  • 2 eggs, beaten
  • 1/2 cup heavy cream
  • 2 cups mozzarella cheese
  • 12 slices pepperoni I used uncured, nitrate-free.

Instructions

  • Preheat oven to 350 degrees.
  • Drizzle the olive oil in a skillet on medium-high heat. Add the onions. Cook for 2-3 minutes or until fragrant and translucent. Add in the garlic and stir.
  • Place the ground beef in the skillet along with Italian seasoning, and salt and pepper to taste. Using a meat chopper, break the ground beef into chunks. If you have excess fat on the beef, drain it from the pan.
  • Add the cream cheese and marinara. Cook until the ground beef is no longer pink and the cream cheese has melted.
  • Remove the skillet from heat.
  • In a medium bowl, combine the eggs,  1/2 cup shredded mozzarella, and heavy cream.
  • Spray a 9×13 pan with cooking oil spray if it isn't a nonstick pan.
  • Add the ground beef mixture to the 9×13 casserole dish.
  • Drizzle the egg and cream liquid mixture on top.
  • Sprinkle the remaining 1 1/2 cup shredded mozzarella on top.
  • Add the pepperoni.
  • Bake for 15-20 minutes or until the cheese begins to bubble. I like for the cheese to brown at the corners of the pan. Mine was ready around 17.
  • Cool before serving.

Video

Notes

  • If your ground beef has a lot of fat, drain it from the pan before adding the cream cheese and marinara.
  • Eggs are used as a binder. The dish does not taste like eggs. If you omit the eggs, the casserole will fall apart.
  • If you want the pepperoni visible on top of the casserole, be sure to add the pepperoni after you have added the shredded mozzarella.
  • The casserole will last in the fridge for 3-4 days.
  • Cream isn’t usually an ingredient you want to freeze. I have frozen this casserole, fully cooked. Upon reheating, it was still good, but it did not taste as good as it would if you eat it within a few days.

CASSEROLE SUBSTITUTION TIPS

You can make changes to this dish and switch it up however you like. If you omit the eggs, your casserole will likely fall apart very easily. You can not taste the eggs in this recipe.
  • Ground Turkey
  • Bacon
  • Chicken
  • Green Peppers
  • Olives
  • Mushrooms
Recipe Tools Used in this RecipeAs an Amazon Associate I earn from qualifying purchases.

Nutrition (displayed with net carbs)

Serving: 1serving | Calories: 449kcal | Carbohydrates: 4g | Protein: 30g | Fat: 34g
Easy Keto Chicken RecipesCheck out 20 Keto Low-Carb Chicken Recipes here!
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Nutrition DataMacros are provided as a courtesy and should not be construed as a guarantee. This information is calculated using MyFitnessPal.com. To obtain the most accurate nutritional information in a given recipe, you should calculate the nutritional information with the actual ingredients used in your recipe, using your preferred nutrition calculator. You are solely responsible for ensuring that any nutritional information provided is accurate, complete, and useful.
4.88 from 31 votes
Recipe Rating




Nancy Billeiter

Wednesday 6th of November 2024

Wow! This recipe is great ! My Husband is on a low carb/keto diet and he loved this, he thought it had crust ! We really enjoyed it !

staysnatched

Friday 8th of November 2024

Wonderful!

Will

Monday 4th of December 2023

If you double the recipe will you still double the heavy cream?

staysnatched

Friday 8th of December 2023

You double all of the ingredients.

Becca

Friday 16th of June 2023

Does this freeze well?

staysnatched

Friday 16th of June 2023

It has dairy. Anytime you freeze dairy it separates when you reheat it. It depends on if separation bothers you.

Deborah

Friday 24th of February 2023

Winner for us. Made as written. Might mix up toppings next time. Thank you. Will make again for sure.

staysnatched

Friday 24th of February 2023

So glad to hear it!

Heather

Wednesday 18th of January 2023

I have been craving pizza nonstop recently and this recipe is the perfect solution for that when counting calories and trying to eat high protein. Easy to make - love how easy it is to reduce the calories/fat (e.g., if not doing keto) by swapping in lower-fat beef and cream cheese - and delicious! Gotta love being able to quickly satisfy a pizza craving without just ordering pizza (high cost and calorie!).

staysnatched

Thursday 19th of January 2023

So glad to hear!